Saturday, April 10, 2010

A look back at iPS: "they could have caught up in a flash"

Appearing in a comment thread on the Sticklen plagiarism matter is a post about stem cells.

Towards a Balanced View on iPS Cells (Logical Biology 8 (1):32-38, 2008; LINK

Stem cells: 5 things to know before jumping on the iPS bandwagon (Nature 452: 406-408, 2008, LINK )

Read more: Plagiarism retracts review - The Scientist - Magazine of the Life Sciences

Stem cells: 5 things to know before jumping on the iPS bandwagon IPBiz notes that among the five things, Nature neglected to mention the Bayer patents. Nature did have the following:

Despite some scepticism about iPS cells, many key researchers embrace them as a preferred alternative to embryonic stem cells. “Only time will tell, but I know where I'm going,” says Thomson, who was the first to establish human embryonic stem-cell lines in 1998. If things go as he predicts, it could be the end of an era. “If you can't tell the difference between iPS cells and embryonic stem cells, the embryonic stem cells will turn out to be a historical anomaly,” he says.


When Shinya Yamanaka and his postdoctoral student Kazutoshi Takahashi from Kyoto University in Japan discovered that four genes could reprogram adult mouse cells, they kept it secret for nearly six months. They stopped having weekly laboratory meetings, and Takahashi fibbed to colleagues about the status of his work. All because the process is so simple. “If someone found out, they could have caught up in a flash,” he says. [IPBiz note: in fact, Bayer scientists had already come up with the idea!]

See previous IPBiz post:

Patent to Sakurada iPS in Britain


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